Water → HCID 86741452, compound

HRID 543106Notes

Reaction equation

HRID 543106 reaction equation
[P:1]([O-:8])([O:5]CC)[O:2]CC.O.[CH2:10]([O:14][CH2:15][CH2:16][CH2:17][NH2:18])[CH2:11][CH2:12][CH3:13]>C(O)C>[CH2:10]([P:1](=[O:2])([O-:5])[O-:8])[CH3:11].[CH2:10]([O:14][CH2:15][CH2:16][CH2:17][NH3+:18])[CH2:11][CH2:12][CH3:13].[CH2:10]([O:14][CH2:15][CH2:16][CH2:17][NH3+:18])[CH2:11][CH2:12][CH3:13]

Participants

5

Reactant 3

HCID 962WaterHCID 854611-Propanamine, 3-butoxy-HCID 3780918Diethylphosphite

Product 1

HCID 86741452HCID 86741452, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A mixture of 13.81 g. (0.1 moles) of diethyl phosphite, 20 ml. of water and 20 ml. of ethanol is reacted with a mixture of 13.12 g. (0.1 moles) of 3-butyloxypropyl amine and 30 ml. of ethanol as described in Example 1. 23.1 g. of 3-butyloxypropyl-ammoniumethyl phosphonate are obtained. Yield: 95.7%. nD30 =1.4438

Workup

  1. additionA mixture of 13.81 g

Sources & evidence

ORD record
ord-6d630da99e0f4fa49a9dcd640ea85048
Source dataset
uspto-grants-1987_04
Patent number
US04661477

Reaction notes

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