Water → HCID 86741453, compound

HRID 543108Notes

Reaction equation

HRID 543108 reaction equation
[P:1]([O-:6])([O:4]C)[O:2]C.O.[CH:8]1([NH2:13])[CH2:12][CH2:11][CH2:10][CH2:9]1>CO>[CH3:8][P:1](=[O:6])([O-:4])[O-:2].[CH:8]1([NH3+:13])[CH2:12][CH2:11][CH2:10][CH2:9]1.[CH:8]1([NH3+:13])[CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

5

Reactant 3

HCID 962WaterHCID 2906CyclopentylamineHCID 21884954Dimethylphosphite

Product 1

HCID 86741453HCID 86741453, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A mixture of 11 g. (0.1 moles) of dimethyl phosphite, 20 ml. of water and 20 ml. of methanol is reacted with a mixture of 8.51 g. (0.1 moles) of cyclopentyl amine and 30 ml. of methanol as described in Example 1. 18.0 g. of cyclopentyl ammoniummethyl phosphonate are obtained.

Workup

  1. additionA mixture of 11 g

Sources & evidence

ORD record
ord-92e92f3d70ae4851877bf1b954e43126
Source dataset
uspto-grants-1987_04
Patent number
US04661477

Reaction notes

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