HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → HCID 13606717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | 3-(4-benzylpiperazin-1-yl)propan-1-amine | HCID 3149269 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13606717 | HCID 13606717 | 61% |
Reaction Steps
A solution of 1-(3-aminopropyl)-4-benzylpiperazine (3.0 g; 12.9 mmole) and phenyl isocyanate (1.54 g; 12.9 mmole) in methylene chloride (20 ml) was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, and the residue was crystallized from aqueous acetone to provide the title compound as colorless crystals (2.77 g; 61% yield), m.p. 45°-47° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04661481 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-8435f83c8ec1469abc27feada329723f |
| Source note | uspto-grants-1987_04 |