p-Toluenesulfonic acid → HCID 20206179, 화합물

HRID 543309노트

반응식

HRID 543309 반응식
[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH2:5][CH2:6][C:7]([C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][C:11]=1[OH:17])([CH3:9])[CH3:8].[CH2:19](O)[CH2:20][CH2:21][CH2:22][CH2:23]C.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[OH:17][C:11]1[CH:12]=[C:13]([OH:16])[CH:14]=[CH:15][C:10]=1[C:7]([CH3:9])([CH3:8])[CH2:6][CH2:5][CH2:4][C:3]([O:2][CH2:1][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:18]

참가 물질

4

반응물 3

HCID 6101p-Toluenesulfonic acidHCID 81031-HexanolHCID 20206153HCID 20206153, 화합물

생성물 1

HCID 20206179HCID 20206179, 화합물

실험 절차

5.5 Parts of methyl-5-(2',4'-dihydroxyphenyl)-5-methyl-hexanoate, 50 parts of n-hexanol, and 0.5 parts of p-toluene sulphonic acid are heated on a steam-bath for 6 hours. The excess hexanol is then removed under reduced pressure and the residual oil taken up in ether, washed with sodium bicarbonate solution, water, and evaporated. Short path distillation of the residual oil at 0,7 mbar yields 5.8 parts of n-hexyl 5-(2',4'-dihydroxyphenyl)-5-methyl-hexanoate of the formula ##STR16## with the following percentage composition by weight:

후처리

  1. customThe excess hexanol is then removed under reduced pressure
  2. washwashed with sodium bicarbonate solution, water
  3. customevaporated
  4. distillationShort path distillation of the residual oil at 0,7 mbar

출처 및 근거

ORD 기록
ord-194f93ec7a5b4e2babd66a26a3a5ee61
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04661601

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