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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 543360Generated: October 31, 2026

Benzenamine, 3,5-bis(trifluoromethyl)- → Trans-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclohexane carboxylic acid

https://huagongshe.com/reaction/543360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant(-)-trans-1,2-Cyclohexanedicarboxylic AnhydrideHCID 12261141—
ProductTrans-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclohexane carboxylic acidHCID 13376244—

Reaction Steps

Using, as starting materials, 2.3 g of 3,5-bistrifluoromethyl aniline, and 1.5 g (0.01 mole) of trans-cyclohexane-1,2-dicarboxylic anhydride, the title compound was obtained in the same manner as in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04661630
Source datasetuspto-grants-1987_04
ORD IDord-e83c038485cb43acb26f69a95920d2d4
Source noteuspto-grants-1987_04