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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 543363Generated: October 26, 2026

Benzenamine, 3,5-bis(trifluoromethyl)- → Cis-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclobutane carboxylic acid

https://huagongshe.com/reaction/543363

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant3-Oxabicyclo(3.2.0)heptane-2,4-dioneHCID 138261—
ProductCis-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclobutane carboxylic acidHCID 18607497—

Reaction Steps

From 2.3 g of 3,5-bistrifluoromethyl aniline and 1.1 g of cyclobutane-1,2-dicarboxylic anhydride used as starting materials, the title compound was obtained in the same manner as in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04661630
Source datasetuspto-grants-1987_04
ORD IDord-8c65be023f484ca0861d6823bc2f684c
Source noteuspto-grants-1987_04