HCID 18607495, compound → HCID 23706402, compound

HRID 543365Notes

Reaction equation

HRID 543365 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]1[CH:4]=[C:5]([NH:13][C:14]([C@H:16]2[CH2:21][CH2:20][CH2:19][CH2:18][C@H:17]2[C:22]([OH:24])=[O:23])=[O:15])[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[OH-].[Na+:28].CO>>[F:1][C:2]([F:25])([F:26])[C:3]1[CH:4]=[C:5]([NH:13][C:14]([C@H:16]2[CH2:21][CH2:20][CH2:19][CH2:18][C@H:17]2[C:22]([O-:24])=[O:23])=[O:15])[CH:6]=[C:7]([C:9]([F:12])([F:10])[F:11])[CH:8]=1.[Na+:28]

Participants

3

Reactant 2

HCID 18607495HCID 18607495, compoundHCID 23721981Sodium hydroxide methanol

Product 1

HCID 23706402HCID 23706402, compound

Procedure

10 m Mol of cis-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclohexane carboxylic acid was dissolved in 100 ml of 0.1N NaOH/methanol solution. The solvent was evaporated off to dryness to give sodium cis-2-[(3,5-bistrifluoromethyl phenyl)-aminocarbonyl]-cyclohexane carboxylate [melting point: 259°-260° C. (decomposition)].

Workup

  1. customThe solvent was evaporated off to dryness

Sources & evidence

ORD record
ord-9f2bf8faa2b04c1fb43a61988fdfed31
Source dataset
uspto-grants-1987_04
Patent number
US04661630

Reaction notes

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