Potassium → HCID 6604391, compound

HRID 543487Notes

Reaction equation

HRID 543487 reaction equation
[CH3:1][C:2]1([CH3:32])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@@H:13]([NH2:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([O:23][CH2:24][O:25][C:26]([C:28]([CH3:31])([CH3:30])[CH3:29])=[O:27])=[O:22].Cl.[K]>O>[CH3:1][C:2]1([CH3:32])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@@H:13]([NH2:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([O:23][CH2:24][O:25][C:26]([C:28]([CH3:31])([CH3:30])[CH3:29])=[O:27])=[O:22]

Participants

4

Reactant 2

HCID 5462222PotassiumHCID 76313488HCID 76313488, compound

Product 1

HCID 6604391HCID 6604391, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred solution of pivampicillin hydrochloride (2.50 g, 5 mmol) in water (100 ml) was added dropwise 0.1 M aqueous potassium 6β-bromopenicillanate (50 ml). The colorless precipitate thus obtained was filtered off, washed with water (3×10 ml), and dried in vacuo to give the pure title compound as colorless crystals which began to decompose at 120°-130° C. without melting.

Workup

  1. customThe colorless precipitate thus obtained
  2. filtrationwas filtered off
  3. washwashed with water (3×10 ml)
  4. customdried in vacuo

Sources & evidence

ORD record
ord-93dbbc3076374857ad387c82772d0410
Source dataset
uspto-grants-1984_05
Patent number
US04446144

Reaction notes

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