HRID543518

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C[C@@H]1[C@H]2CC(=O)O[C@H]2C[C@H]1OC(=O)c1ccccc1

HCID11000244

Corey aldehyde benzoate

C15H14O5

HCID13269867

Dimethyl (3-methyl-2-oxooct-5-yn-1-yl)phosphonate

C11H19O4P

PRODUCTS

生成物

结构：CCC#CCC(C)C(=O)/C=C/[C@@H]1[C@H]2CC(=O)O[C@H]2C[C@H]1OC(=O)c1ccccc1

HCID13472481

未命名化合物

收率 90%

PROCEDURE

实验过程

Analogously to Example 1(g), 14.2 g of the title compound was synthesized from 9.85 g of 3-methyl-2-oxooct-5-inylphosphonic acid dimethyl ester and 11 g of (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3,3,0]octan-3-one [E. J. Corey et al., J. Amer. Chem. Soc. 91: 5675 (1969)].