Methyl iodide → HCID 12898280, compound

Participants

Reaction Steps

1 ml of 3-benzyl-4-hydroxy-biphenyl polyglycol ether, as an emulsifier, and 995 g (5 mol) of 6-sec.-butyl-4-methyl-5-oxo-3-thioxo-tetrahydro-1,2,4(2H,4H)-triazine (IX) were added to a solution of 202 g of NaOH in 5 liters of water. 724 g (5.1 mol) of methyl iodide were added dropwise and the mixture was subsequently stirred until the slightly exothermic reaction had ended and the pH value had reached 7-8. After filtering off the product, washing it with water and drying it at 30° C. in vacuo, 907 g (85% of theory) of the compound (IIb) of melting point 45°-50° C. were obtained. The crude product was sufficiently pure for further reaction. A sample recrystallised from pentane melted at 54°-55° C.

Provenance & Evidence