Water → HCID 68866327, compound

Participants

Reaction Steps

Kiliani's reagent (100 ml) was added slowly to a solution of 3-methyl-5α-androst-2-en-17β-ol (43 g) in acetone (170 ml). When the addition was complete, water was added to give a precipitate, which was filtered off. The product was redissolved in acetone and water was again added. The precipitate was filtered off, washed with water and dried to give 3-methyl-5α-androst-2-en-17-one (35.7 g). A sample was recrystallised from ether-light petroleum (40°-60°) and from ether to give pure material, m.p. 124°-126°; [α]D +141° (c 0.48 in EtOH).

Provenance & Evidence