反应详情

2-Methylthio-5-ethoxycarbonyl-4-hydroxypyrimidine (2.5 mmol, 535 mg) was refluxed overnight in ethanol with n-octylamine (4 mmol, 650 μl). The product was filtered off and washed with ethanol. Yield 402 mg (54.5%)

1. filtrationThe product was filtered off
2. washwashed with ethanol