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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 543683Generated: October 31, 2026

Formaldehyde → HCID 178487717, compound

https://huagongshe.com/reaction/543683

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 178487715HCID 178487715—
SolventSodium HydroxideHCID 14798—
ProductHCID 178487717HCID 178487717—

Reaction Steps

4-Hydroxy-7-methoxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide (initially at 40°-50°, then kept at 60° for 18 hours) to give the novel compound 4-hydroxy-3-hydroxymethyl-7-methoxyquinoline, m.p. 291°-297°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04447435
Source datasetuspto-grants-1984_05
ORD IDord-e1e06d6477df4cfcb0d5d6b9e28c2c08
Source noteuspto-grants-1984_05