Formaldehyde → HCID 178519791, compound

HRID 543694Notes

Reaction equation

HRID 543694 reaction equation
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:12])=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1.[CH2:13]=[O:14]>[OH-].[Na+]>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:12])=[C:7]([CH2:13][OH:14])[CH:8]=[N:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 178418765HCID 178418765, compound

Product 1

HCID 178519791HCID 178519791, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

7-Bromo-4-hydroxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 7-bromo-4-hydroxy-3-hydroxymethylquinoline, m.p. >300°

Sources & evidence

ORD record
ord-fc8fccc548f2499bad0d80d0021712a7
Source dataset
uspto-grants-1984_05
Patent number
US04447435

Reaction notes

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