Methanol → HCID 13285862, compound

Participants

Reaction Steps

Prepared analogously to Example 7(c) from 5,10-dihydro-5-[(2,6-dimethyl-4-pyridinyl)carbonyl]-11H-dibenzo[b,e][1,4]diazepin-11-one methoiodide and sodium borohydride in methanol in a yield of 25% of theory. After purification by column chromatography on silica gel using dichloromethane/methanol (ratio by volume 9:1) as a eluent and recrystallizing from diisopropylether/methanol, the light beige crystals melted at 124°-125° C.

Provenance & Evidence