4-(4-Chlorophenyl)-4-(dimethylamino)cyclohexan-1-one → HCID 53705284, compound

HRID 543861Notes

Reaction equation

HRID 543861 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([N:22]([CH3:27])[CH2:23][CH2:24][CH2:25][CH3:26])[CH2:20][CH2:19][C:18](=[O:21])[CH2:17][CH2:16]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:29]1C=CC(C2(N(C)C)CCC(=O)CC2)=CC=1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2([N:22]([CH2:23][CH2:24][CH2:25][CH3:26])[CH3:27])[CH2:16][CH2:17][C:18](=[O:21])[CH:19]([CH3:29])[CH2:20]2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 125956504-(4-Chlorophenyl)-4-(dimethylamino)cyclohexan-1-oneHCID 20380029HCID 20380029, compound

Product 1

HCID 53705284HCID 53705284, compound

Procedure

Following the procedure of Preparation VIIA but substituting 4-(m-benzyloxyphenyl)-4-n-butylmethylamino)cyclohexanone (prepared according to Preparation VI) for 4-(p-chlorophenyl)-4-dimethylaminocyclohexanone there is obtained 4-(m-benzyloxyphenyl)-4-(n-butylmethylamino)-2-methylcyclohexanone.

Workup

  1. customthe procedure of Preparation VIIA

Sources & evidence

ORD record
ord-f06aaeb078e245e89d659f6ef31d5cd1
Source dataset
uspto-grants-1984_05
Patent number
US04447454

Reaction notes

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