HCID 20461139, compound → HCID 86739398, compound

HRID 543879Notes

Reaction equation

HRID 543879 reaction equation
[BrH:1].[C:2]([CH2:5][CH:6]1[S:15][C:9]2=[N:10][CH2:11][N:12]([CH3:14])[CH2:13][N:8]2[C:7]1([C:17]1[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=1)[OH:16])([OH:4])=[O:3]>CO>[CH3:2][O-:3].[BrH:1].[C:2]([CH2:5][CH:6]1[S:15][C:9]2=[N:10][CH2:11][N:12]([CH3:14])[CH2:13][N:8]2[C:7]1([C:17]1[CH:18]=[CH:19][C:20]([Cl:23])=[CH:21][CH:22]=1)[OH:16])([OH:4])=[O:3]

Participants

3

Reactant 1

HCID 20461139HCID 20461139, compound

Product 1

HCID 86739398HCID 86739398, compoundYield 186.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

7-Carboxymethyl-6-(p-chlorophenyl)-6-hydroxy-3-methyl-3,4,6,7-tetrahydro-2H-thiazolo[3,2-a]-s-triazine hydrobromide (2 g) was redissolved in the minimum quantity of methanol and immediately recrystallised to give 7-carboxymethyl-6-(p-chlorophenyl)-6-hydroxy-3-methyl-3,4,6,7-tetrahydro-2H-thiazolo[3,2-a]-s-triazine hydrobromide methanolate as colourless crystals (2.0 g), m.p. 138° C.

Workup

  1. customimmediately recrystallised

Sources & evidence

ORD record
ord-7ee328bd2b01492fb4bd2cd1a7df0fe4
Source dataset
uspto-grants-1984_05
Patent number
US04447604

Reaction notes

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