Triazinthion → HCID 86739399, compound

Participants

Reaction Steps

A solution of 3-bromo-3-(m-nitrobenzoyl)propionic acid (7.55 g, 0.024 mole) in methanol (50 ml) was mixed with a solution of 5-methyl-3,4,5,6-tetrahydro-s-triazine-2(1H)thione (3.27 g, 0.025 mole) in the same solvent (170 ml). After 3 hours at room temperature the solvent was evaporated to small volume when a colourless solid crystallised, which was collected to give 7-carboxymethyl-6-hydroxy-3-methyl-6-(m-nitrophenyl)-3,4,6,7-tetrahydro-2H-thiazolo[3,2-a]-s-triazine hydrobromide methanolate (7.5 g), m.p. 144°-145° C. (decomposition).

Provenance & Evidence