HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanol → 2-(2-Aminothiazol-4-yl)-2-propargyloxyiminoacetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanol | HCID 887 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Ethyl 2-(2-aminothiazol-4-yl)-2-propargyloxyiminoacetate | HCID 53907014 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-(2-Aminothiazol-4-yl)-2-propargyloxyiminoacetic acid | HCID 54372682 | 77,3% |
Reaktionsschritte
Ethyl 2-(2-aminothiazol-4-yl)-2-propargyloxyiminoacetate (syn isomer, 2.8 g.), methanol (23 ml.), tetrahydrofuran (20 ml.) and 1 N aqueous solution of sodium hydroxide (22.17 ml.) were treated in a similar manner to that of Example F-(4) to give 2-(2-aminothiazol-4-yl)-2-propargyloxyiminoacetic acid (syn isomer, 1.924 g.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04447430 |
| Quelldatensatz | uspto-grants-1984_05 |
| ORD ID | ord-f87a04eb1ca84d148621f11d3effb4af |
| Quellennotiz | uspto-grants-1984_05 |