HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 13306691, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine | HCID 47795 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 13306691 | HCID 13306691 | — |
Reaction Steps
3-Amino-1-(3-trifluoromethylphenyl)-2-pyrazoline (1.907 g) (prepared as described in European Pat. No. 0022570) was dissolved in formic acid (20 ml). The solution was stirred at 60° and acetic anhydride (2.4 ml) added dropwise. The mixture was heated for 1 hour at 60° and then poured into water and stirred to decompose the residual excess anhydride. 3-Formamido-1-(3-trifluoromethylphenyl)-2-pyrazoline resulted as a crystalline solid m.p. 128°-129°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04448783 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-6ccd0dc7762c44c7b2649db5aa8276be |
| Source note | uspto-grants-1984_05 |