Ammonia → HCID 70478252, compound

HRID 544112Notes

Reaction equation

HRID 544112 reaction equation
C([O:3][C:4](=O)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]2[NH:15][CH:16]=[CH:17][N:18]=2)=[CH:9][C:8]=1[O:19][CH3:20])C.[NH3:22]>>[NH:18]1[CH:17]=[CH:16][N:15]=[C:14]1[CH2:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([NH2:22])=[O:3])=[C:8]([O:19][CH3:20])[CH:9]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 70478121HCID 70478121, compound

Product 1

HCID 70478252HCID 70478252, compound

Procedure

Treatment of 4-(1-imidazolylmethyl)-2-methoxyphenoxyacetic acid ethyl ester with ammonia as described in Example 8 gave 4-(1-imidazolylmethyl)-2-methoxyphenoxyacetamide, m.p. 124°-125° C. (from chloroform/petrol). Found: C, 59.39, H, 5.83, N, 16.07. C13H15N3O3 requires: C, 59.75, H, 5.78, N, 16.08%.

Sources & evidence

ORD record
ord-9837269317c846629fba5ca1fee545a6
Source dataset
uspto-grants-1984_05
Patent number
US04448781

Reaction notes

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