Ammonia → HCID 70477808, compound

HRID 544116Notes

Reaction equation

HRID 544116 reaction equation
C([O:3][C:4](=O)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:8]=1[CH2:14][C:15]1[NH:16][CH:17]=[CH:18][N:19]=1)C.[NH3:21]>>[Cl:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([NH2:21])=[O:3])=[C:8]([CH2:14][C:15]2[NH:16][CH:17]=[CH:18][N:19]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 70478691HCID 70478691, compound

Product 1

HCID 70477808HCID 70477808, compound

Procedure

Treatment of 4-chloro-2-(1-imidazolylmethyl)phenoxyacetic acid ethyl ester with ammonia as described in Example 8 gave 4-chloro-2-(1-imidazolylmethyl)phenoxyacetamide, m.p. 162°-164° C. (from isopropanol/petrol). Found: C, 53.91, H, 4.51, N, 15.79. C12H12ClN3O2 requires: C, 54.23, H, 4.57, N, 15.81%.

Sources & evidence

ORD record
ord-0b31a1d2165642a5af1acfb0ebc5be21
Source dataset
uspto-grants-1984_05
Patent number
US04448781

Reaction notes

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