Benzhydrylamine → HCID 20459477, compound

Participants

Reaction Steps

A mixture of 18.3 g of benzhydrylamine, 10 g of triethylamine and 60 ml of acetonitrile is added dropwise to a boiling mixture of 13.2 g of 1,4-bis-(bromomethyl)-benzene in 60 ml of acetonitrile. The mixture is left to boil overnight, is greatly concentrated, and partitioned between 200 ml of ether and 200 ml of 10% sodium hydroxide solution, concentrated by evaporation and recrystallised from diethyl ether. N,N'-bis-(diphenylmethyl)-p-xylylenediamine having a melting point of 92°-94° C. is obtained.

Provenance & Evidence