反应详情

A solution of 2.9 g of benzyl chloride in 25 ml of acetonitrile is added to 5.6 g of N-diphenylmethyl-ethylenediamine in 30 ml of boiling acetonitrile. The mixture is heated under reflux for 12 hours, concentrated and partitioned between diethyl ether and 10% sodium hydroxide solution. The organic phases are dried over sodium sulphate and concentrated by evaporation. The residue can be recrystallised from methanol or diisopropyl ether. N,N-dibenzyl-N'-diphenylmethyl-ethylenediamine having a melting point of 89°-91° C. is obtained.

1. temperatureThe mixture is heated
2. temperatureunder reflux for 12 hours
3. concentrationconcentrated
4. custompartitioned between diethyl ether and 10% sodium hydroxide solution
5. dry with materialThe organic phases are dried over sodium sulphate
6. concentrationconcentrated by evaporation
7. customThe residue can be recrystallised from methanol or diisopropyl ether