反应详情

To 7 ml of tetralin is added 1.5 g of α-cyano-β-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide, and this mixture is heated to 180°-200° under nitrogen for 30 minutes. After cooling, the resulting solid is filtered, washed with pentane, slurried with acetone/hexane and again filtered to give 1-(2,4,6-trichloroanilino)-5-cyano-2,4-pyrimidinedione, m.p.>320°.

1. temperaturethis mixture is heated to 180°-200° under nitrogen for 30 minutes
2. temperatureAfter cooling
3. filtrationthe resulting solid is filtered
4. washwashed with pentane
5. filtrationagain filtered