Tetrafluoroboric acid → HCID 13326266, compound

HRID 544208Notes

Reaction equation

HRID 544208 reaction equation
N([O-])=O.[Na+].N[C:6]1[N:11]([NH:12][C:13]2[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=2[CH3:20])[C:10](=[O:21])[NH:9][C:8](=[O:22])[CH:7]=1.[H+].[B-](F)(F)(F)[F:25]>O>[F:25][C:6]1[N:11]([NH:12][C:13]2[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=2[CH3:20])[C:10](=[O:21])[NH:9][C:8](=[O:22])[CH:7]=1

Participants

5

Reactant 3

HCID 28118Tetrafluoroboric acidHCID 13326264HCID 13326264, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 13326266HCID 13326266, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Sodium nitrite (1.1 mole) dissolved in water is slowly added to a cool (0°-5°) solution of 6-amino-1-(2,6-dimethylanilino)-2,4-pyrimidinedione (1 mole) in dilute fluoboric acid. The precipitate which forms is filtered off, washed with water, dried and pyrolyzed under nitrogen (only a small amount at a time) to give 6-fluoro-1-(2,6-dimethylanilino)-2,4-pyrimidinedione.

Workup

  1. additionis slowly added to
  2. filtrationThe precipitate which forms is filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-fba7bb5b0e5c4914ae6b074df200f43d
Source dataset
uspto-grants-1984_05
Patent number
US04448961

Reaction notes

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