HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → 5-Phenyloxazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Ethyl 2-hydroxy-2-phenylethanimidate--hydrogen chloride (1/1) | HCID 12387918 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 5-Phenyloxazolidine-2,4-dione | HCID 84042 | — |
Reaction Steps
By the procedure of Example 3, except that a reaction time of 16 hours at room temperature was used following cold perfusion with phosgene, ethyl 1-hydroxy-1-phenylmethanecarboximidate hydrochloride (22 g., 0.102 mole) in 450 ml. of tetrahydrofuran was converted to toluene recrystallized 5-phenyloxazolidine-2,4-dione (10.5 g., m.p. 103°-105° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04448971 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-709f2981513f418982411cfaa2b42b97 |
| Source note | uspto-grants-1984_05 |