HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylpropylamine → HCID 14234525, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylpropylamine | HCID 16259 | — |
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- | HCID 85083 | — |
| Product | HCID 14234525 | HCID 14234525 | 52.4% |
Reaction Steps
By the method of part A of Example 1 N-(tert-butyloxycarbonyl)-L-proline (4.3 g.) was condensed with 3-phenylpropylamine (2.7 g.) and the product was purified by high pressure liquid chromatography on silica gel using hexaneethyl acetate (7:3) as the eluant, affording 1-(tert-butyloxycarbonyl)-N-(3-phenylpropyl)-L-prolinamide (3.48 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04450155 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-22f777dac3a94aefa7c129a83763b088 |
| Source note | uspto-grants-1984_05 |