Sulfuric Acid → HCID 13078512, compound

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Reaction Steps

The carboxylic acid, 3-[[[(pentafluorophenyl)amino]thioxomethyl]thio]propionic acid (500 mg., 1.51 mmol) is dissolved in acetic anhydride (5 ml.) to give a bright yellow solution. A drop of conc. H2SO4 is added and the solution heated on a steam bath for 2-3 minutes. On cooling, crystals separated, which are recrystallized from ethanol to give pure 3-(pentafluorophenyl)tetrahydro-2-thioxo-4H-1,3-thiazin-4-one as bright yellow translucent crystals (320 mg.) m.p. 163.5°-164.5°.

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