HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 544384Generated: October 31, 2026
4-Chloroaniline → 4-(4-Chloroanilino)-6,7-dihydro-5H-cyclopenta[d]pyrimidine
https://huagongshe.com/reaction/544384
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 4-chloro-5H,6H,7H-cyclopenta[d]pyrimidine | HCID 13312449 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-Chloroanilino)-6,7-dihydro-5H-cyclopenta[d]pyrimidine | HCID 13121208 | — |
Reaction Steps
To 3.1 g (0.02 mole) of 4-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine were added 5.1 g (0.04 mole) of p-chloroaniline and about 10 ml of ethanol; the mixture was then heated at 130° C. for 5-10 minutes. The reaction mixture quickly became a solution and then produced crystals of the hydrochloride of the desired product on being allowed to cool.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04450162 |
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| Source dataset | uspto-grants-1984_05 |
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| ORD ID | ord-04fa9bdc49184e98b94e0820ebf64cb3 |
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| Source note | uspto-grants-1984_05 |
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