HCID 131713512, compound → HCID 178469529, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the oil of Step A and 70 ml of phenyl oxide was stirred under an inert atmosphere and was then heated at 250° C. for one hour while distilling the formed ethanol. The mixture was cooled and 30 ml of acetone were added thereto. The mixture was vacuum filtered and the product was empasted with 30 ml of acetone and was dried and crystallized from ethanol to obtain 36 g of ethyl 4-hydroxy-6-ethyl-3-quinoline-carboxylate melting at >260° C.

Provenance & Evidence