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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 544398Generated: November 1, 2026

Diethyl (ethoxymethylene)malonate → HCID 178469553, compound

https://huagongshe.com/reaction/544398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (ethoxymethylene)malonateHCID 6871—
ReactantDiphenyl EtherHCID 7583—
Reactant4-FluoroanilineHCID 9731—
ProductHCID 178469553HCID 178469553—

Reaction Steps

Using the procedure of Example 2, ethyl ethoxymethylene malonate and 4-fluoro-aniline were reacted and treated with phenyl oxide to obtain ethyl 6-fluoro-4-hydroxy-3-quinoline-carboxylate melting at >260° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04450166
Source datasetuspto-grants-1984_05
ORD IDord-d9300caa764b4c8d970fb59ddb28ccbe
Source noteuspto-grants-1984_05