HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3-Cyano-methyl-2-methyl-8-(2-phenylethyl)imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Amino-3-(2-phenylethyl)pyridine | HCID 13900235 | — |
| Reactant | 3-Chloro-4-oxopentanenitrile | HCID 13900236 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Cyano-methyl-2-methyl-8-(2-phenylethyl)imidazo[1,2-a]pyridine | HCID 70505979 | — |
Reaction Steps
In similar manner, reaction of 2-amino-3-(2-phenylethyl)pyridine (which is prepared by amination of 3-(2-phenyl ethyl)-pyridine with sodium amide in ammonia and N,N-dimethylaniline) with 3-chloro-4-oxo-pentanonitrile in ethanol in the presence of triethylamine gives 3-cyano-methyl-2-methyl-8-(2-phenylethyl)imidazo[1,2-a]pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04450164 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-382b7b5ab5964d11afc889f3a014c562 |
| Source note | uspto-grants-1984_05 |