Benzyl Chloride → 2-Amino-3-phenylmethoxy-4-methlylpyridine

HRID 544476Notes

Reaction equation

[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([CH3:9])[CH:5]=[CH:4][N:3]=1.[CH2:10](Cl)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH2:1][C:2]1[CH:7]([O:8][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:6](=[CH2:9])[CH:5]=[CH:4][N:3]=1

Participants

Reactant 2

HCID 7503Benzyl Chloride

HCID 5800542-Amino-4-methyl-3-pyridinol

Product 1

HCID 1317135132-Amino-3-phenylmethoxy-4-methlylpyridine

Procedure

2-amino-3-phenylmethoxy-4-methlylpyridine was prepared as an oil by reacting 2-amino-3-hydroxy-4-methylpyridine with benzyl chloride followingthe procedures of Example 1, Step A herein.

Sources & evidence

ORD record: ord-49e62f1029f141b28933da07f40c18e3
Source dataset: uspto-grants-1984_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04450164

Reaction notes

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