HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone Cyanohydrin → 4-Piperidinecarbonitrile, 4-hydroxy-2,2,6,6-tetramethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone Cyanohydrin | HCID 6406 | — |
| Reactant | 2,2,6,6-Tetramethyl-4-piperidone | HCID 13220 | — |
| Product | 4-Piperidinecarbonitrile, 4-hydroxy-2,2,6,6-tetramethyl- | HCID 90874 | — |
Reaction Steps
A solution of 97 g 2,2,6,6-tetramethyl-4-piperidone and 67 g of acetone cyanohydrin were stirred at room temperature for 30 hours to precipitate the desired cyanohydrin. The precipitate was collected, washed with petroleum ether and air dried to yield 70 g (61.4%); mp 129°-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04450248 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-7878704355e2418a93dc77d151aea8d1 |
| Source note | uspto-grants-1984_05 |