Sodium Methoxide → HCID 15586993, compound

HRID 544528Notes

Reaction equation

HRID 544528 reaction equation
[CH3:1][N:2]1[C:7](SC)=[N:6][C:5](=[O:10])[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH3:17])[CH:12]=2)=[N:3]1.[CH3:18][O-:19].[Na+]>CO>[CH3:1][N:2]1[C:7]([O:19][CH3:18])=[N:6][C:5](=[O:10])[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH3:17])[CH:12]=2)=[N:3]1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 12831831HCID 12831831, compound

Product 1

HCID 15586993HCID 15586993, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 2-methyl-3-methylthio-6-(m-methylphenyl)-5-oxo-2,5-dihydro-1,2,4-triazine (1.0 g) in methanol (10 ml), sodium methoxide (0.5 g) was added, and the resultant mixture was stirred at room temperature for 2 hours. After stirring, the resulting mixture was evaporated to dryness to give a crude product. Recrystallization of the crude product from acetone gave 0.85 g of 2-methyl-3-methoxy-6-(m-methylphenyl)-5-oxo-2,5-dihydro-1,2,4-triazine in 91% yield. M.P., 110° C.

Workup

  1. customthe resulting mixture was evaporated to dryness
  2. customto give a crude product
  3. customRecrystallization of the crude product from acetone

Sources & evidence

ORD record
ord-48ea47363b654ff9932dd544ca807763
Source dataset
uspto-grants-1984_05
Patent number
US04451283

Reaction notes

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