HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 10487008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-2-oxo- | HCID 77919 | — |
| Reactant | Potassium amide | HCID 87015 | — |
| Product | HCID 10487008 | HCID 10487008 | — |
Reaction Steps
Boatman et al [J. Org. Chem. 30, 3593-7 (1965)] show the reaction of 3-cyano-6-methyl-2(1H)-pyridinone with potassium amide in liquid ammonia and subsequent reaction of the resulting salt with methyl iodide to produce 3-cyano-6-ethyl-2(1H)-pyridinone (p. 3596, 3a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04451469 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-f7f054c0d09f49babcbc2ab646ff77a7 |
| Source note | uspto-grants-1984_05 |