Acetic Acid → HCID 20458212, compound

HRID 544570Notes

Reaction equation

HRID 544570 reaction equation
[OH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:11]=[C:10]([NH2:12])[CH:9]=[CH:8][N:7]=1.[CH3:13][C:14](O)=[O:15]>C(OC(=O)C)(=O)C>[C:14]([O:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:11]=[C:10]([NH2:12])[CH:9]=[CH:8][N:7]=1)(=[O:15])[CH3:13]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 20458264HCID 20458264, compound

Product 1

HCID 20458212HCID 20458212, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A mixture of 2-(2-hydroxyethylthiomethyl)-4-aminopyrimidine (1.5 g.) in HOAc (5 ml.) and acetic anhydride (5 ml.) was stirred at 25° for 16 hours. The solvent was evaporated in vacuo to give 2-(2-acetoxyethylthiomethyl)-4-aminopyrimidine as a gum which was used without further purification.

Workup

  1. customThe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-97a92f0e5b9e48ae89a8b206418db1c2
Source dataset
uspto-grants-1984_05
Patent number
US04451463

Reaction notes

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