1,1,1-Trifluoro-2-isothiocyanatoethane → HCID 86739433, compound

HRID 544582Notes

Reaction equation

HRID 544582 reaction equation
[NH2:1][C:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][OH:14])[CH:8]=2)[N:3]=1.[F:15][C:16]([F:22])([F:21])[CH2:17][N:18]=[C:19]=[S:20]>C(#N)C>[F:15][C:16]([F:22])([F:21])[CH2:17][NH:18][C:19](=[S:20])[NH:1][C:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][OH:14])[CH:8]=2)[N:3]=1

Participants

4

Reactant 2

HCID 138837771,1,1-Trifluoro-2-isothiocyanatoethaneHCID 20458260HCID 20458260, compound

Product 1

HCID 86739433HCID 86739433, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of this sample of unpurified 4-amino-2-(3-hydroxymethylphenyl)-1,2,3-triazole, 2,2,2-trifluoroethylisothiocyanate (0.202 g.) and acetonitrile (5 ml.) was kept at room temperature overnight. The mixture was evaporated to leave a residue of unpurified 4-[3-(2,2,2-trifluoroethyl)thioureido]-2-(3-hydroxymethylphenyl)-1,2,3-triazole which was used without further purification.

Workup

  1. customThe mixture was evaporated

Sources & evidence

ORD record
ord-a5bf06d91c60411cb3e935f31e4ca73f
Source dataset
uspto-grants-1984_05
Patent number
US04451463

Reaction notes

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