4-Chlorobenzenesulfenylchloride → 3-(4-Chlorophenylthio)-5-phenoxymethyloxazolidin-2-one

HRID 544585Notes

Reaction equation

HRID 544585 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]Cl)=[CH:4][CH:3]=1.[O:10]([CH2:17][CH:18]1[O:22][C:21](=[O:23])[NH:20][CH2:19]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][N:20]2[CH2:19][CH:18]([CH2:17][O:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[O:22][C:21]2=[O:23])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 110844654-ChlorobenzenesulfenylchlorideHCID 157171415-(Phenoxymethyl)-1,3-oxazolidin-2-one

Product 1

HCID 204584183-(4-Chlorophenylthio)-5-phenoxymethyloxazolidin-2-oneYield 33%

Procedure

Analogously to Example 4, 33% yield of 3-(4-chlorophenylthio)-5-phenoxymethyloxazolidin-2-one with a melting point of 98° to 101° C. was obtained from 4-chlorophenylsulphenyl chloride and 5-phenoxymethyloxazolidin-2-one.

Sources & evidence

ORD record
ord-b6ebfa734eb34e1581cc1831b8088c99
Source dataset
uspto-grants-1984_05
Patent number
US04451475

Reaction notes

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