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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 544613Generated: October 29, 2026

Methanol → 5-[7-(4-Methoxycarbonylphenoxy)heptyl]-3-methylisoxazole

https://huagongshe.com/reaction/544613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant5-[7-(4-Carboxyphenoxy)heptyl]-3-methylisoxazoleHCID 5271209—
Product5-[7-(4-Methoxycarbonylphenoxy)heptyl]-3-methylisoxazoleHCID 527119495%

Reaction Steps

[I; R is CH3, n is 7, X is O, Ar is 4--CH3OOCC6H4 ], m.p. 60° C. in 95% yield from 5-[7-(4-carboxyphenoxy)heptyl]-3-methylisoxazole (Example 16) and methanol; MIC vs. rhinovirus Type 2 in vitro=3 μg/ml.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04451476
Source datasetuspto-grants-1984_05
ORD IDord-63bc71c90bc14664920e18a329aba2e5
Source noteuspto-grants-1984_05