HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 544614Generated: October 30, 2026
Hydrazine hydrate (1:1) → HCID 5271196, compound
https://huagongshe.com/reaction/544614
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Ethyl 4-{[7-(3-methyl-1,2-oxazol-5-yl)heptyl]oxy}benzoate | HCID 5271190 | — |
| Product | HCID 5271196 | HCID 5271196 | — |
Reaction Steps
A mixture of 3.0 g (0.086 mole) of 5-[7-(4-ethoxycarbonylphenoxy)heptyl]-3-methylisoxazole (Example 22) and 10 ml of hydrazine hydrate was heated at reflux for six hours. The reaction mixture was cooled to 0° C. whereupon the solid product separated. The latter was collected, washed and dried in vacuo to give 2.6 g of 5-[7-(4-hydrazinocarbonylphenoxy)heptyl]-3-methylisoxazole, m.p. 121°-122° C., MIC vs. rhinovirus Type 2 in vitro=0.64 μg/ml.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04451476 |
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| Source dataset | uspto-grants-1984_05 |
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| ORD ID | ord-b53cb35b13b84965aa8235e922a25aab |
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| Source note | uspto-grants-1984_05 |
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