Sulfuric Acid → HCID 20458453, compound

Participants

Reaction Steps

A mixture of 4.0 g. of 3-amino-1-(p-fluorophenyl)-5-methyl-2-pyrazoline (prepared as described in Example 26), 25.0 ml. of water and 1.0 ml. of concentrated sulfuric acid is refluxed for 6 hours. The mixture is cooled and the precipitate is collected and the solid is recrystallized first from acetone-hexane, then from acetone to give 1.0 g. of the desired product as prisms, m.p. 164.5°-166.5° C.

Provenance & Evidence