HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → 2-[4,5-Bis-(p-methoxyphenyl)-thiazol-2-ylthio]acetaldehyde-ethyleneacetal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 2-[4,5-Bis-(p-methoxyphenyl)-thiazol-2-ylthio]-acetaldehyde | HCID 13209672 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-[4,5-Bis-(p-methoxyphenyl)-thiazol-2-ylthio]acetaldehyde-ethyleneacetal | HCID 20458371 | — |
Reaction Steps
0.2 g of 2-[4,5-bis-(p-methoxyphenyl)-thiazol-2-ylthio]acetaldehyde are dissolved in 50 ml of toluene. While stirring vigorously, 1 ml of ethylene glycol and then 0.2 g of p-toluenesulphonic acid are added. The mixture is heated for 40 hours in a water separator, cooled to 20°, filtered with suction, crystallised from hexane/benzene and dried under reduced pressure to constant weight. 2-[4,5-bis-(p-methoxyphenyl)-thiazol-2-ylthio]acetaldehyde-ethyleneacetal is obtained in the form of a viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04451471 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-0c3224f005164834ad91c7ba5f55fffe |
| Source note | uspto-grants-1984_05 |