2-(Dimethylamino)ethanol → HCID 53677118, compound

HRID 544703Notes

Reaction equation

HRID 544703 reaction equation
[N:1]([C:4]1[CH:14]=[CH:13][C:7]([CH:8]=[CH:9][C:10](Cl)=[O:11])=[CH:6][CH:5]=1)=[N+:2]=[N-:3].[CH3:15][N:16]([CH3:20])[CH2:17][CH2:18][OH:19]>C(Cl)(Cl)(Cl)Cl>[N:1]([C:4]1[CH:14]=[CH:13][C:7]([CH:8]=[CH:9][C:10]([O:19][CH2:18][CH2:17][N:16]([CH3:20])[CH3:15])=[O:11])=[CH:6][CH:5]=1)=[N+:2]=[N-:3]

Participants

4

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 541587253-(4-Azidophenyl)prop-2-enoyl chloride

Product 1

HCID 53677118HCID 53677118, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

In carbon tetrachloride was dissolved 14 g (70 millimoles) of the p-azidocinnamic acid chloride obtained in Example 16, and 6 g (70 millimoles) of 2-dimethylaminoethanol was added dropwise to the resulting solution at 10° to 20° C., after which the resulting mixture was allowed to react for 1 hour. The deposited precipitate was collected by filtration, and 100 ml of water was added thereto.

Workup

  1. additionwas added dropwise to the resulting solution at 10° to 20° C.
  2. customto react for 1 hour
  3. filtrationThe deposited precipitate was collected by filtration, and 100 ml of water
  4. additionwas added

Sources & evidence

ORD record
ord-de0b25277116422686d3a4c037f266b4
Source dataset
uspto-grants-1984_05
Patent number
US04451551

Reaction notes

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