Acetyl chloride → HCID 54330111, compound

Participants

Reaction Steps

42.6 ml (0.6 mole) of acetyl chloride are added dropwise in the course of 1 hour at room temperature, while stirring, to 81.1 g (0.5 mole) of 4-methyl-2-(1-methyl-2-propenyl)-phenol. The reaction mixture is then heated to 100° and left at this temperature for 2 hours. After cooling, water is cautiously added and extraction is carried out with methylene chloride. The organic phase is dried over sodium sulphate and concentrated by evaporation. Subsequent distillation of the remaining residue (64°-70°/4.10-2 torr) yields 4-methyl-2-(1-methyl-2-propenyl)-phenyl acetate in the form of a pale-yellow oil.

Provenance & Evidence