4-Iodobenzoyl chloride → 4-Bromo-3-(4-iodophenylmethyl)-1-(beta-D-glucopyranosyl)indole

Beteiligte Stoffe

Reaktionsschritte

The titled compound was prepared from 4-bromo-1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)indole obtained in Example 22-(1) and 4-iodobenzoyl chloride in a manner similar to Example 27 as a colorless powder. APCI-Mass m/Z 574/576 (M-+H). 1H-NMR (DMSO-d6) δ 3.20-3.50 (m, 4H), 3.62-3.71 (m, 2H), 4.25 (s, 2H), 4.54 (t, J=5.5 Hz, 1H), 5.10 (d, J=5.3 Hz, 1H), 5.17 (d, J=5.0 Hz, 1H), 5.22 (d, J=5.8 Hz, 1H), 5.41 (d, J=9.2 Hz, 1H), 7.02 (d, J=8.2 Hz, 2H), 7.04 (t, J=8.2 Hz, 1H), 7.21 (d, J=7.4 Hz, 1H), 7.32 (s, 1H), 7.60 (d, J=8.2 Hz, 1H), 7:61 (d, J=8.2 Hz, 2H).

Herkunft & Nachweise