huagongshe.com
HRID544938

反应详情

EQUATION

反应方程式

HRID 544938 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccc(Cl)cc1
HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1csc(Br)c1
HCID59761487

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1csc(-c2ccc(Cl)cc2)c1
HCID24985911

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by coupling 5-bromo-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)thiophene-3-carboxamide a with commercially available 4-chlorophenylboronic acid using the method described in Step B of Example 136 to afford a white solid (Example 201). HPLC Ret time=3.67 min. LCMS [M+H]+ 411.221.

WORKUP

后处理

  1. customto afford a white solid (Example 201)
  2. customHPLC Ret time=3.67 min