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HRID544941

反应详情

EQUATION

反应方程式

HRID 544941 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccc(Cl)cc1
HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(Br)cs1
HCID59761499

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(-c2ccc(Cl)cc2)cs1
HCID24985913

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by coupling 4-bromo-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)thiophene-2-carboxamide a with commercially available 4-chlorophenylboronic acid using the method described in Step B of Example 136 to afford a white solid (Example 203). HPLC Ret time=3.66 min. LCMS [M+H]+ 411.221.

WORKUP

后处理

  1. customto afford a white solid (Example 203)
  2. customHPLC Ret time=3.66 min