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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 544994Generated: October 27, 2026

HCID 66934671, compound → 4-(9-Chloro-5,7-dimethyl-6-oxo-6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepin-2-ylamino)-benzoic acid

https://huagongshe.com/reaction/544994

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66934671HCID 66934671—
ReactantHCID 178512548HCID 178512548—
Product4-(9-Chloro-5,7-dimethyl-6-oxo-6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepin-2-ylamino)-benzoic acidHCID 57663153—

Reaction Steps

In a manner similar to that described for method I, 8-chloro-4-dimethylaminomethylene-1,3-dimethyl-3,4-dihydro-1H-benzo[b]azepine-2,5-dione (v-o) and 4-guanidinobenzoic acid were converted to I-68 (6%) after purification by C-18 RP LC-MS chromatography: HRMS Calcd. for C21H17ClN4O3: 409.1067, Found 409.1052.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935694B2
Source datasetuspto-grants-2011_05
ORD IDord-77a215b1fda84946be8cde78707adddf
Source noteuspto-grants-2011_05